After graduating from Istanbul University Faculty of Dentistry in 1989, Ahmet Keles started the orthodontic residency program at Harvard University İn United States with the scholarship of the Ministry of Education. In 1994, he completed his doctorate degree, and his thesis study received the best research award offered by American Association of Orthodontics.

After completing his doctorate, he taught orthodontics at Marmara University. After obtaining his postdoctoral degree in 2002, he served as clinical director of orthodontics at University of Connecticut from 2003 to 2005. In 2005, he started teaching at Harvard University. He is stil going to United States for teaching postgraduate students, and he is seeing patients in his private practice in Istanbul.

Ahmet Keles has many patents Keles Slider, Keles Face Mask and Keles Expander, his inventions bearing his name are produced and widely used in United States. He is giving courses and seminars all over the world from United States to Australia. He developed his last patent Keles Keyless Expander with his son Eren Keles. He has authored more than 50 scientific publications and many orthodontic textbook chapters. He was the Editor of World Journal of Orthodontics.